Characterization of 17 strains belonging to the Mycobacterium simiae complex and description of Mycobacterium paraense sp. nov.

نویسندگان

  • Ana R Fusco da Costa
  • Tarcisio Fedrizzi
  • Maria L Lopes
  • Monica Pecorari
  • Wana L Oliveira da Costa
  • Elisabetta Giacobazzi
  • Jeann R da Costa Bahia
  • Veronica De Sanctis
  • Karla V Batista Lima
  • Roberto Bertorelli
  • Antonella Grottola
  • Anna Fabio
  • Alessandro Mariottini
  • Pamela Ferretti
  • Francesca Di Leva
  • Giulia Fregni Serpini
  • Sara Tagliazucchi
  • Fabio Rumpianesi
  • Olivier Jousson
  • Nicola Segata
  • Enrico Tortoli
چکیده

Fourteen mycobacterial strains isolated from pulmonary samples of independent patients in the state of Pará (Brazil), and three strains isolated in Italy, were characterized using a polyphasic approach. Thorough genetic investigation, including whole-genome sequencing, demonstrated that the strains belong to the M. simiae complex, being most closely related to Mycobacterium interjectum. For 14 of the strains, evidence emerged supporting their inclusion in a previously unreported species of the genus Mycobacterium, for which the name Mycobacterium paraense sp. nov. is proposed (type strain, IEC26(T) = DSM 46749(T) = CCUG 66121(T)). The novel species is characterized by slow growth, unpigmented or pale yellow scotochromogenic colonies, and a HPLC mycolic acid profile different from other known mycobacteria. In different genetic regions, high sequence microheterogeneity was detected.

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عنوان ژورنال:
  • International journal of systematic and evolutionary microbiology

دوره 65 Pt 2  شماره 

صفحات  -

تاریخ انتشار 2015